Sunday, March 31, 2019
18:00 – 19:30
Registration/Information
19:30 – 21:00
Opening Dinner
Monday, April 1, 2019
8:30 – 17:00
Registration/Information
8:45 – 9:00
Opening Remarks
Tamar Schlick, New York University, USA
Session I
Tamar Schlick, New York University, USA, Chair
9:00 – 9:30
Mair Churchill, University of Colorado, Denver, USA
Histone Trafficking During Chromatin Replication
9:30 – 10:00
Ivet Bahar, University of Pittsburgh, USA
Chromatin Dynamics Studied by the Gaussian Network Model: Short- and Long-Range Couplings Between Gene Loci
10:00 – 10:30
Anna Panchenko, NCBI, NIH, USA
Integrating in Silico and in Vitro Approaches to Characterize Nucleosome Structure and Dynamics with High Precision
10:30 – 11:00
Coffee Break
Session II
Helmut Schiessel, Leiden University, The Netherlands, Chair
11:00 – 11:30
Garegin Papoian, University of Maryland, USA
Structural Plasticity of Histone Oligomers and Their Interactions with Chaperones and Other Regulators
11:30 – 11:50
Alexey Onufriev, Virginia Tech, USA*
DNA Accessibility Control in the Nucleosome: Insights from Physics
11:50 – 12:10
Jürgen Walther, IRB Barcelona, Spain*
From DNA to Chromatin: Multiscale Models from Atomistic to KB Level
12:30 – 13:30
Lunch Break
13:30 – 17:00
Networking
Session III
Lars Nordenskiöld, Nanyang Technological University, Singapore, Chair
17:00 – 17:30
Helmut Schiessel, Leiden University, The Netherlands
The Mechanical Genome
17:30 – 18:35
Poster Pitches
19:00 – 19:30
Welcome Reception
19:30 – 21:00
Dinner
21:00 – 22:00
Poster Session I
Tuesday, April 2, 2019
8:30 – 17:00
Registration/Information
Session IV
Thomas Bishop, Louisiana Tech University, USA Chair
9:00 – 9:30
Mark Ellisman, University of California, San Diego, USA
Imaging Local and Global Chromatin Structure as a 3D Continuum within the Nucleus: Progress and Future Strategies
9:30 – 10:00
Ariel Kaplan, Technion - Israel Institute of Technology, Israel
Nucleosome Diffusion and Gene Expression Regulation: Insights from Single Molecule Studies
10:00 – 10:30
Thomas Bishop, Louisiana Tech University, USA
Genome Dashboards: Framework and G-Dash Prototype
10:30 – 11:00
Coffee Break
Session V
Jie Yan, Mechanobiology Institute, National University of Singapore, Singapore, Chair
11:00 – 11:20
Madhura De, Heidelberg University, Germany*
Positioning the Linker Histone on a Chromatosome: What Role Does the DNA Play?
11:20 – 11:40
Anat Galis Vivante, Bar Ilan University, Israel*
Chromatin Dynamics Governed by a Set of Nuclear Structural Proteins
11:40 – 12:00
Hugo van Ingen, Utrecht University, The Netherlands*
Capturing Interactions to the Nucleosome Acidic Patch by Multi-Scale NMR
12:30 – 13:30
Lunch Break
13:30 – 17:40
Networking
Session VI
Andrzej Stasiak, University of Lausanne, Switzerland, Chair
17:45 – 18:05
Catherine Royer, Rensselaer Polytechnic Institute, USA*
Superresolution Imaging of the Start Transcription Factors
18:05 – 19:05
Poster Pitches
19:30 – 21:00
Dinner
21:00 – 22:00
Poster Session II
Wednesday, April 3, 2019
8:30 – 17:00
Registration/Information
Session VII
Garegin Papoian, University of Maryland, USA, Chair
9:00 – 9:30
Hitoshi Kurumizaka, University of Tokyo, Japan
Structural Studies of Chromatin: Toward Understanding the Regulation of Genomic DNA
9:30 – 10:00
Jie Yan, Mechanobiology Institute, National University of Singapore, Singapore
Transfer-Matrix Calculation of the Effects of Physical Constraints Applied to DNA on DNA-Protein Interactions
10:00 – 10:30
Tamar Schlick, New York University, USA
Folding Genes at Nucleosome Resolution
10:30 – 11:00
Coffee Break
Session VIII
Hitoshi Kurumizaka, University of Tokyo, Japan, Chair
11:00 – 11:20
Pablo D. Dans Puiggròs, IRB Barcelona, Spain*
Understanding Gene Regulation Through the 3D Structure of Chromatin and Chromosomes
11:20 – 11:40
Joshua Moller, University of Chicago, USA*
Unveiling Chromatin Fiber Condensation Through Many-Body Nucleosome Interactions
11:40 – 12:00
Marina Katava, University of Texas at Austin, USA*
Unveiling Chromatin Fiber Condensation Through Many-Body Nucleosome Interactions
12:30 – 13:30
Lunch Break
13:30 – 17:45
Networking
Session IX
Mair Churchill, University of Colorado, Denver, USA, Chair
17:45 – 18:15
Lars Nordenskiöld, Nanyang Technological University, Singapore
Structure and Dynamics of the Telomeric Nucleosome and Chromatin
18:15 – 18:35
Quinn MacPherson, Stanford University, USA*
Heterochromatin and the Nuclear Periphery: Specificity via Density
18:35 – 19:05
Toshio Tsukiyama, Fred Hutchinson Cancer Research Center, USA
Mechanisms and Functions of Chromatin Condensation in Quiescent Yeast Cells
19:30 – 21:00
Dinner
21:00 – 22:00
Poster Session III
Thursday, April 4, 2019
8:30 – 17:00
Registration/Information
Session X
G.V. Shivashankar, Mechanobiology Institute, National University of Singapore, Singapore , Chair
9:00 – 9:30
Amartya Sanyal, Nanyang Technological University, Singapore
Connecting Genomic and Non-Genomic Mechanisms of Cancer Drug Resistance
9:30 – 10:00
Angelo Rosa, International School for Advanced Studies, Italy
From Chromosome Territories to Ring Polymers: Physical Properties of Untangled Polymer Melts
10:00 – 10:30
Alexandra Zidovska, New York University, USA
The "Self-Stirred" Genome: Bulk and Surface Dynamics of the Chromatin Globule
10:30 – 11:00
Coffee Break
Session XI
Erez Lieberman-Aiden, Baylor College of Medicine, USA, Chair
11:00 – 11:20
Artemi Bendandi, University of Genoa, Italy*
Mesoscale Bottom-Up Approach to the Study of Chromatin Topological Conformations: From the Nucleosome to 1Mbps
11:20 – 11:40
Soya Shinkai, RIKEN, Center for Biosystems Dynamics Research, Japan*
Deciphering Hi-C Data into Polymer Dynamics
11:40 – 12:00
Michele Di Pierro, Rice University, USA*
The Three-Dimensional Architecture of the Human Genome: It’s Nuclear Physics!
12:30 – 13:30
Lunch Break
13:30 – 17:45
Networking
Session XII
Amartya Sanyal, Nanyang Technological University, Singapore, Chair
17:45 – 18:15
G.V. Shivashankar, Mechanobiology Institute, National University of Singapore, Singapore
Mechanical Control of Chromosome Organization and Gene Expression
18:15 – 18:45
Erez Lieberman-Aiden, Baylor College of Medicine, USA
A 3D Code in the Human Genome
18:45 – 19:05
Anne Shim, Northwestern University, USA*
The Crowded Nanoenvironment Influences Gene Expression
19:30 – 21:00
Dinner
21:00 – 22:00
Poster Session IV
Friday, April 5, 2019
8:30 – 13:30
Information
Session XIII
John van Noort, Leiden University, The Netherlands, Chair
9:00 – 9:30
Andrzej Stasiak, University of Lausanne, Switzerland
TADs and chromatin supercoiling
9:30 – 10:00
Vlad Cojocaru, Max-Planck Institute for Molecular Biomedicine, Germany
How Do DNA-Binding Proteins Interpret and Modify Nucleosome Dynamics?
10:00 – 10:30
Coffee Break
Session XIV
Alexandra Zidovska, New York University, USA, Chair
10:30 – 11:00
John van Noort, Leiden University, the Netherlands
Chromatin Higher Order Folding in Irregular Fibers: A Critical Role of Linker DNA
11:00 – 11:30
Wilma Olson, Rutgers University, USA
Contributions of Nucleosome Architecture to Long-Range Communication on Chromatin
11:30 – 12:00
Closing Remarks and Biophysical Journal Poster Awards
Thomas Bishop, Louisiana Tech University, USA
12:30 – 13:30
Lunch
*Short talks selected from among submitted abstracts