/ Tuesday, March 7, 2017 / Categories: All Videos, Biophysics 101 Biophysics 101- Cryo-electron microscopy (Cryo-EM) 01:13:24 This video can only be viewed by current BPS members Are you a member? Login to Watch Not a member yet? Become a Member Cryo electron microscopy is booming, with new atomic structures appearing every week and new facilities being installed at research centers across the globe. This unprecedented growth has been stimulated by the availability of new imaging detectors that dramatically increase the acuity of images, but also reflects advances in electron microscopes and image analysis software. These technologies are being employed for two main applications, known as single-particle analysis and tomography, which can be used to produce structures of a wide range of biomolecular assemblies, from isolated molecules to cells and tissues. This Biophysics 101 session discusses both the technologies and the applications to provide insight into why cryo-EM has become such a powerful and essential tool in structural biology. Presenters: David DeRosier, Brandeis University Esther Bullitt, Boston University School of Medicine Go Back Previous Video Biophysics 101 - Kieth Lidke Next Video Biophysics 101: Förster resonance energy transfer (FRET) 5226 Tags: Structural Biology cryo-EM Brandeis University Biophysics 101 Cryo electron microscopy atomic structures single-particle analysis tomography biomolecular assemblies David DeRosier Esther Bullitt Boston University School of Medicine Related articles Biophysics 101 - Membrane Model Systems: Nanodiscs, Giant Vesicles, and Simulations Biophysics 101 - Incorporating Bayesian Inference and Artificial Intelligence Approaches into Biophysics Biophysics 101 - The Physics of Epigenetics at the Nucleosome Level Biophysics 101: Introduction to Molecular Dynamics Simulations and Its Applications to Biological Systems Biophysics 101: Mechanobiology Comments are only visible to subscribers.