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Molecular Dynamics Simulations of Lipid Bilayers
Simulations from the Scott Feller Laboratory at Wabash College. This site provides, among other things, PDB coördinates of lipid bilayers produced by molecular dynamics simulations.
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Molecular Dynamics Simulations of POPC
Helmut Heller, of the Leibniz-Rechenzentrum in Munich, provides molecular dynamics simulations of POPC in various phases.
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Lipid Bilayer Membranes for RasMol
This page at the University of Massachusetts PDB files are available for 1-palmitoyl 2-oleoyl phosphatidyl choline bilayers (200 molecules total), hydrated with about 15 layers of water on each side, for various configurations.
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Transport Protein Database
The Saier Laboratory Bioinformatics Group at UCSD provides the TC-DB website, which details a comprehensive classification system for membrane transport proteins known as the Transport Commission (TC) system. The TC system is analogous to the Enzyme Commission (EC) system for classification of enzymes, except that it incorporates both functional and phylogenetic information. Descriptions, TC numbers, and examples of over 300 families of transport proteins are provided.
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Protein Sequence Analysis And Modeling (PSAAM) Software
This package, from the University of Illinois, contains a main program (PSAAM), and several ancillary programs (INFORMAT, calculates mean sequence profiles and mutability moment (conservation moment) from aligned sequences; FINDSEQ, will find sequence strings (structural motifs, binding domains, etc.) in a sequence file, or a directory of sequence files; GENBANK, will extract sequence data from a file saved from Entrez).
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Membrane Protein Secondary Structure Prediction
The purpose of this server at the University of Split, Croatia, is to predict the transmembrane (TM) secondary structures of membrane proteins, using the method of preference functions.
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Protein Data Bank
The Protein Data Bank from the Research Collaboratory for Structural Bioinformatics (RCSB)
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PDB Reports at EMBL
Comprehensive report of errors in PDB files from the Sander group at Heidelberg.
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PIR the Protein Information Resource
An integrated protein information resource for genomic and proteomic research. Provides access to UniProt (Universal Protein Resource).
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Swiss-Prot: an Annotated Protein Sequence Database from ExPASy
Swiss-Prot provides a high level of annotations such as: the description of the function of a protein, its domains structure, and post-translational modifications, variants, etc. There is a minimal level of redundancy and a high level of integration with other databases.
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NCBI Structure Group at the NIH
Included are links to NCBI's MMDB - Molecular Modeling DataBase, PubVast, PubChem, and conserved domain database (CDD).
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RasMol Molecular Visualization at the University of Massachusetts
RasMol is a molecular graphics program intended for the visualisation of proteins, nucleic acids and small molecules. The program is aimed at display, teaching and generation of publication quality images. The program has been developed at the University of Edinburgh's Biocomputing Research Unit and the Biomolecular Structure Department at Glaxo Research and Development, Greenford, UK.
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DeepView - Swiss-PDBViewer for Visualization of Protein Structures at ExPASy
DeepView - Swiss-PdbViewer is an application that provides a user friendly interface allowing to analyse several proteins at the same time. The proteins can be superimposed in order to deduce structural alignments and compare their active sites or any other relevant parts. Amino acid mutations, H-bonds, angles and distances between atoms are easy to obtain thanks to the intuitive graphic and menu interface.
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GenBank at the National Center for Biotechnology Information
Search MEDLINE, protein databases, and nucleotide databases using Entrez Browser with forms-based or non-forms based clients.
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HIV Sequence Database at the Los Alamos National Laboratory
The Human Retroviruses and Aids Database collects, curates, analyzes, and publishes genetic sequences of the human immunodeficiency virus (HIV) and related species.
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National Center for Genome Resources
NCGR offers an integrated biological knowledge system facilitating organized accessibility, integration, and analysis of different biological data types. This system provides the research community with a framework for determining the function of gene sequences.
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Center for Biological Sequence Analysis
A research site with a goal to obtain knowledge of the complex relations between sequence composition and macromolecular structure and function. The research is aimed at creating entirely new possibilities in the study of evolutionary processes by comparison of sequence patterns across species. The work of the center focuses in particular on a number of novel data driven and adaptive computational methods, which are not created on the basis of assumptions and known facts, but for example by trai
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SCOP from MRC
SCOP organizes the Brookhaven PDB according to secondary, tertiary, and other structural features. It is produced at MRC Laboratory of Molecular Biology and the Cambridge Center for Protein Engineering.
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Principles of Protein Structure from Birkbeck College
This is a course available on the Internet which is sponsored by Birkbeck College. The course uses a wide range of interactive and multimedia techniques to bring high-quality, low-cost learning to students throughout the world. The course is intended for scientists who need to know more about how and why protein structure is central to modern biology. The Protein Structure Course Announcement provides a course outline for committed scientists in disciplines such as chemistry, molecular
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Protein Motions a Protein Data Bank Listing
This describes the motions that occur in proteins and other macromolecules, particularly using movies. Associated with it are a variety of free software tools and servers for structural analysis.
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European Bioinformatics Institute (EBI)
EBI is an Outstation of the European Molecular Biology Laboratory. Links to the Human Genome Mapping Project and Nucleotide Sequence and several Protein Sequence Databases as well as Sequence Similarity Searches and Database query and retrieval are available.
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ExPASy : Bioformatics Resource Portal
ExPASy is an extensible and integrative portal accessing many scientific resources, databases and software tools in different areas of life sciences.
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BioZon
A unified biological resource on DNA sequences, proteins, complexes and cellular pathways.
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Brenda - Comprehensive Enzyme Information System
Contains functional information for nearly 5,000 enzymes.
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ChemSpider
ChemSpider is a free chemical structure database providing fast text and structure search access to over 58 million structures from hundreds of data sources.
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PubChem
Find chemical structures, assay data points, and descriptive data about small molecules.
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TOXNET
Find information on toxicology, environmental health, hazardous chemicals, and toxic releases.