Mechanobiology is an emerging area of biophysics that focuses on the role of mechanical cues that alter cellular responses and their transduction by cells. Topics ranging from rigidity sensing by stem cells to osmosensing in bacteria are all based upon mechanochemical processes. This Subgroup will call attention to how mechanical aspects of biological functions are critical for shaping organisms and influencing cellular processes at the molecular level. Cellular properties are not merely defined by their components, but how these components interact physically with one another and the cellular microenvironment over time. The Subgroup also offers an annual Early Career Award in Mechanobiology.