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New BJ Cover Doesn't Sacrifice Science for Aesthetics New BJ Cover Doesn't Sacrifice Science for Aesthetics

New BJ Cover Doesn't Sacrifice Science for Aesthetics

Anonym 0 3493

This issue's cover doesn't look like the beautiful protein structures or micrographs that often grace the front of Biophysical Journal—it might just look like layers of brightly-colored candy. But it is drawn from real data and represents a real (and really colorful) biophysical system: the photosynthetic light-harvesting and charge conversion apparatus in stacked thylakoid membranes. 

Tags: photosynthesisThermodynamicsMonte Carlo
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Aspuru-Guzik Group's Art Lights Up BiophysJ Cover

Anonym 1 3442
Alán Aspuru-Guzik and his group in the Department of Chemistry and Chemical Biology at Harvard University describe the image they created for the cover of the current issue of Biophysical Journal. Photosynthesis is the fundamental biological process in many organisms for the energy conversion from sunlight into other forms to be used in cellular processes. Recent experiments have provided evidence that interesting quantum coherence effects persist in several plant, algae, and bacterial ...
Tags: biophysicschlorophyllenergy transportFMO complexphotosynthesisProtein Databank
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SAHELI MITRA:

A must read.

Coronavirus Structure, Vaccine and Therapy Development
Brennan Weaver:

Pretty nice read. I wish I could have written something about Pi. It's my 2nd favorite number value. Also, I don't think Pi is as mysterious as everyone thinks it is. It's just a number with a lot of personalities. And I do believe there is a last digit.

Pi Is Encoded in the Patterns of Life
Harel Weinstein:

Just perused the article "From Dynamics to Membrane Organization- Experimental Breakthroughs Occasion a ‘‘Modeling Manifesto’’ in the August 21 issue. While the Perspective is intriguing, the sheer Chutzpah of writing a "manifesto" about a field of modeling with lists of "demands" based on experiments that in many cases are more limited in scope or reality than any physics-based model, is quite astounding. Neither artificial membrane slabs, nor "live cells" imaged under conditions in which cells have a shabby life that doesn't last long (how much of this is due to the mistreatment of the membrane proteins?) share established behaviors that must be matched or else.... No experiment, computational or using imaging, is meant to mimic reality, only to probe it based on models and assumptions that can be falsified.

As to the role of the cytoskeleton, what does this tell us about the membrane itself, or the behavior of membrane proteins as individual molecules in their interplay with the membrane? And since this unrelated scaffold differs greatly between cells, what is the "correct matching standard"? All models are wrong, some (computational, or on the stage of a microscope) are useful, but in my opinion, self-critical, humble, and rigorous scientific reasoning are preferable to a manifesto in order to foster progress.

In Search of…Protein Interaction Partners
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